6. Lexus LS

The Lexus LS stands out as a luxury sedan that delivers not only comfort and refinement, but also exceptional longevity. Advanced engineering, meticulous assembly, and robust components enable the LS to glide smoothly well beyond 250,000 miles.
According to Autotrader, many LS owners praise its quiet ride and reliable performance, noting that even high-mileage examples feel nearly as solid as new.